regulation of the force of heart contraction by chemical signal hormonal regulation of the force of heart contraction hormonal cardiac inotropy biological_process GO:0003058 hormonal regulation of the force of heart muscle contraction The process in which the hormones modulates the force of heart muscle contraction. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action.