L-glutamate gamma-semialdehyde dehydrogenase activity https://github.com/geneontology/go-ontology/issues/23277 https://github.com/geneontology/go-ontology/issues/30034 1-pyrroline-5-carboxylate dehydrogenase activity Reactome:R-HSA-9929439 pyrroline-5-carboxylate dehydrogenase activity Reactome:R-HSA-6784402 molecular_function 1-pyrroline-5-carboxylate:NAD+ oxidoreductase activity Reactome:R-HSA-70679 (S)-1-pyrroline-5-carboxylate is in spontaneous equilibrium with its tautomer L-glutamate gamma-semialdehyde. The activity can also oxidize other 1-pyrrolines, e.g. oxidation of 3-hydroxy-1-pyrroline-5-carboxylate to 4-hydroxyglutamate, and oxidation of (R)-1-pyrroline-5-carboxylate to D-glutamate. EC:1.2.1.88 GO:0003842 pyrroline-5-carboxylic acid dehydrogenase activity MetaCyc:RXN-14116 RHEA:30235 delta1-pyrroline-5-carboxylate dehydrogenase activity L-pyrroline-5-carboxylate-NAD+ oxidoreductase activity 1-pyrroline dehydrogenase L-glutamate 5-semialdehyde + NAD+ + H2O = L-glutamate + NADH + 2 H+. oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor