6-phosphofructo-2-kinase activity https://github.com/geneontology/go-ontology/issues/30193 EC:2.7.1.105 6-phosphofructo-2-kinase (phosphorylating) RHEA:15653 ATP:D-fructose-6-phosphate 2-phosphotransferase activity MetaCyc:6-PHOSPHOFRUCTO-2-KINASE-RXN phosphofructokinase 2 activity 6-phosphofructose 2-kinase activity molecular_function Catalysis of the reaction: beta-D-fructose 6-phosphate + ATP = beta-D-fructose 2,6-bisphosphate + ADP + 2 H+. fructose 6-phosphate 2-kinase activity ATP:beta-D-fructose-6-phosphate 2-phosphotransferase activity GO:0003873 KEGG_REACTION:R02732 Reactome:R-HSA-71802 phosphofructokinase activity