acetyl-CoA synthetase activity https://github.com/geneontology/go-ontology/issues/30193 RHEA:23176 Reactome:R-HSA-71735 acetyl coenzyme A synthetase activity acyl-activating enzyme activity acetyl-coenzyme A synthase activity EC:6.2.1.1 acetate-CoA ligase activity acetate to acetyl-CoA acetic thiokinase activity acetate:CoA ligase (AMP-forming) short-chain acyl-coenzyme A synthetase activity acetyl CoA synthase activity acetyl-coenzyme A synthetase activity Reactome:R-HSA-8875071 acetyl CoA ligase activity acetyl-CoA synthase activity MetaCyc:ACETATE--COA-LIGASE-RXN GO:0003987 Catalysis of the reaction: acetate + ATP + CoA = acetyl-CoA + AMP + diphosphate. Reactome:R-HSA-449911 acetate thiokinase activity acetyl-activating enzyme activity short chain fatty acyl-CoA synthetase activity ACS acetyl activating enzyme molecular_function CoA-ligase activity