apyrase activity https://github.com/geneontology/go-ontology/issues/2473 https://github.com/geneontology/go-ontology/issues/28199 https://github.com/geneontology/go-ontology/issues/30193 RHEA:64904 molecular_function Catalysis of the reaction: a ribonucleoside 5'-triphosphate + 2 H2O = a ribonucleoside 5'-phosphate + 2 phosphate. This reaction consists of two distinct successive phosphate-releasing steps, with NDPs as intermediates. Apyrases are active against both di- and triphosphate nucleotides (NDPs and NTPs) and hydrolyze NTPs to nucleotide monophosphates (NMPs). RHEA:64908 EC:3.6.1.5 MetaCyc:RXN-14024 RHEA:36795 GO:0004050 RHEA:77735 RHEA:64896 RHEA:20988 pyrophosphatase activity