arachidonate 5-lipoxygenase activity https://github.com/geneontology/go-ontology/issues/28199 EC:1.13.11.34 leukotriene-A(4) synthase activity RHEA:17961 5Delta-lipoxygenase activity RHEA:17485 Catalysis of the reaction: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = H2O + leukotriene A4. RHEA:32307 arachidonate:oxygen 5-oxidoreductase activity arachidonic 5-lipoxygenase activity arachidonic acid 5-lipoxygenase activity MetaCyc:RXN-8647 GO:0004051 5-delta-lipoxygenase activity MetaCyc:ARACHIDONATE-5-LIPOXYGENASE-RXN leukotriene A4 synthase LTA synthase activity delta(5)-lipoxygenase activity C-5-lipoxygenase activity Note that this is a multi-step reaction. leukotriene-A4 synthase activity molecular_function 5-lipoxygenase activity delta5-lipoxygenase activity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen