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    <!-- http://purl.obolibrary.org/obo/GO_0004175 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/GO_0004175">
        <rdfs:label>endopeptidase activity</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/GO_0004197 -->

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        <rdfs:label>cysteine-type endopeptidase activity</rdfs:label>
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        <ns3:IAO_0000233 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/geneontology/go-ontology/issues/30193</ns3:IAO_0000233>
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        <oboInOwl:id>GO:0004197</oboInOwl:id>
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        <oboInOwl:hasDbXref>Reactome:R-HSA-201629</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9013895</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-201628</oboInOwl:hasDbXref>
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        <oboInOwl:hasDbXref>Reactome:R-HSA-9947908</oboInOwl:hasDbXref>
        <oboInOwl:hasNarrowSynonym>metacaspase activity</oboInOwl:hasNarrowSynonym>
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        <oboInOwl:hasDbXref>Reactome:R-HSA-9947987</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>thiol endopeptidase activity</oboInOwl:hasExactSynonym>
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        <oboInOwl:hasDbXref>Reactome:R-HSA-114259</oboInOwl:hasDbXref>
        <ns3:IAO_0000115>Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.</ns3:IAO_0000115>
        <oboInOwl:hasDbXref>EC:3.4.22.16</oboInOwl:hasDbXref>
        <oboInOwl:hasNarrowSynonym>caspase activity</oboInOwl:hasNarrowSynonym>
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        <oboInOwl:hasDbXref>Reactome:R-HSA-9948146</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>molecular_function</oboInOwl:hasOBONamespace>
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        <oboInOwl:hasDbXref>Reactome:R-HSA-351936</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9693929</oboInOwl:hasDbXref>
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        <oboInOwl:hasDbXref>Reactome:R-HSA-9792568</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MetaCyc:3.4.22.14-RXN</oboInOwl:hasDbXref>
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        <oboInOwl:hasDbXref>Reactome:R-HSA-114261</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9694377</oboInOwl:hasDbXref>
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        <oboInOwl:hasDbXref>Reactome:R-HSA-1236948</oboInOwl:hasDbXref>
        <oboInOwl:hasNarrowSynonym>lysosomal cysteine-type endopeptidase</oboInOwl:hasNarrowSynonym>
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        <oboInOwl:hasDbXref>Reactome:R-HSA-350319</oboInOwl:hasDbXref>
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        <skos:narrowMatch rdf:resource="http://identifiers.org/metacyc.reaction/3.4.22.1-RXN"/>
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        <skos:narrowMatch rdf:resource="http://identifiers.org/metacyc.reaction/3.4.22.16-RXN"/>
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        <skos:narrowMatch rdf:resource="http://identifiers.org/metacyc.reaction/3.4.22.41-RXN"/>
        <skos:exactMatch rdf:resource="http://purl.uniprot.org/enzyme/3.4.22.-"/>
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    <!-- http://purl.obolibrary.org/obo/GO_0008234 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/GO_0008234">
        <rdfs:label>cysteine-type peptidase activity</rdfs:label>
    </Class>
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<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



