protoporphyrin ferrochelatase activity https://github.com/geneontology/go-ontology/issues/23371 https://github.com/geneontology/go-ontology/issues/30193 https://github.com/geneontology/go-ontology/issues/31620 heme synthase activity EC:4.98.1.1 RHEA:22584 iron chelatase activity GO:0004325 heme synthetase activity protoheme ferro-lyase activity KEGG_REACTION:R00310 molecular_function protoheme ferrolyase activity protoheme ferro-lyase (protoporphyrin-forming) ferro-protoporphyrin chelatase activity Catalysis of the reaction: heme B (protoheme) + H+ = Fe(2+) + protoporphyrin IX. ferrochelatase activity MetaCyc:PROTOHEMEFERROCHELAT-RXN Reactome:R-HSA-189465 lyase activity