part of long-chain fatty acid metabolic process long-chain fatty acid-CoA ligase activity https://github.com/geneontology/go-ontology/issues/18967 https://github.com/geneontology/go-ontology/issues/20462 https://github.com/geneontology/go-ontology/issues/25799 https://github.com/geneontology/go-ontology/issues/26445 https://github.com/geneontology/go-ontology/issues/28526 https://github.com/geneontology/go-ontology/issues/31587 RHEA:83203 RHEA:36139 Reactome:R-HSA-193424 long-chain-fatty-acyl-CoA synthetase activity thiokinase RHEA:46208 long chain fatty acyl-CoA synthetase activity Reactome:R-HSA-9734535 Catalysis of the reaction: a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons. Reactome:R-HSA-5696004 RHEA:83035 long-chain fatty acyl coenzyme A synthetase activity RHEA:33651 long-chain acyl CoA synthetase activity Reactome:R-HSA-159425 GO:0004467 stearoyl-CoA synthetase RHEA:33607 RHEA:44212 molecular_function RHEA:44216 Reactome:R-HSA-2046085 Reactome:R-HSA-193407 Reactome:R-HSA-193401 Reactome:R-HSA-193766 acyl-CoA synthetase activity acyl-activating enzyme activity RHEA:52108 RHEA:44200 RHEA:83019 RHEA:44204 RHEA:44208 Reactome:R-HSA-2046098 RHEA:67848 RHEA:52112 RHEA:52116 RHEA:44076 MetaCyc:RXN-7904 RHEA:85307 Reactome:R-HSA-193743 Reactome:R-HSA-192137 long-chain-fatty-acid-CoA ligase activity RHEA:52088 RHEA:30751 RHEA:44084 RHEA:52008 RHEA:83199 RHEA:44220 RHEA:33615 RHEA:44224 Reactome:R-HSA-548843 pristanoyl-CoA synthetase RHEA:15421 lignoceroyl-CoA synthase activity While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283). RHEA:52012 RHEA:52016 RHEA:44192 RHEA:33619 LCFA synthetase activity RHEA:33647 RHEA:83347 RHEA:33643 Reactome:R-HSA-193727 RHEA:44932 RHEA:44936 long-chain acyl-CoA synthetase activity long-chain acyl-coenzyme A synthetase activity acyl-CoA ligase activity fatty acid thiokinase (long-chain) activity RHEA:33635 long-chain fatty acid activation Reactome:R-HSA-193711 Reactome:R-HSA-201035 GO:0003996 RHEA:44092 EC:6.2.1.3 fatty acid-CoA ligase activity