part of protein serine/threonine kinase activity transmembrane receptor protein serine/threonine kinase activity Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. Reactome:R-HSA-201476 EC:2.7.11.30 RHEA:18673 molecular_function Reactome:R-HSA-170868 receptor protein serine/threonine kinase activity Reactome:R-HSA-198732 MetaCyc:2.7.11.30-RXN receptor serine/threonine protein kinase activity GO:0004675 cell surface receptor protein serine/threonine kinase signaling pathway transmembrane receptor protein kinase activity