has part protein serine/threonine kinase activity AMP-activated protein kinase activity Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of AMP. 5'-AMP-activated protein kinase activity protein kinase A activity molecular_function Reactome:R-HSA-200423 Reactome:R-HSA-163691 Reactome:R-HSA-1592244 SNF1A/AMP-activated protein kinase activity Reactome:R-HSA-5673768 Reactome:R-HSA-380927 Reactome:R-HSA-447074 AMPK activity GO:0004679 Reactome:R-HSA-6805470 AMP binding