has part cyclic nucleotide-dependent protein kinase activity cGMP-dependent protein kinase activity https://github.com/geneontology/go-ontology/issues/30193 guanosine 3':5'-cyclic monophosphate-dependent protein kinase activity 3':5'-cyclic GMP-dependent protein kinase activity molecular_function PKG ATP:protein phosphotransferase (cGMP-dependent) activity PKG 1beta Reactome:R-HSA-418442 Reactome:R-HSA-9920025 PKG II cGMP-dependent protein kinase ibeta activity Reactome:R-HSA-418549 STK23 Reactome:R-HSA-1475422 GO:0004692 This reaction requires the presence of cGMP. EC:2.7.11.12 cGMP dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. PKG 1alpha Reactome:R-HSA-1497853 cGMP binding