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    <!-- http://purl.obolibrary.org/obo/GO_0004674 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/GO_0004674">
        <rdfs:label>protein serine/threonine kinase activity</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/GO_0004693 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/GO_0004693">
        <rdfs:label>cyclin-dependent protein serine/threonine kinase activity</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0004674"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0097472"/>
        <ns3:IAO_0000233 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/geneontology/go-ontology/issues/30193</ns3:IAO_0000233>
        <oboInOwl:hasExactSynonym>CDK activity</oboInOwl:hasExactSynonym>
        <oboInOwl:hasBroadSynonym>cyclin-dependent protein kinase activity</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasRelatedSynonym>cdk-activating kinase activity</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>Reactome:R-HSA-187520</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9929719</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-2245218</oboInOwl:hasDbXref>
        <oboInOwl:hasNarrowSynonym>cyclin-dependent kinase-4 activity</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasDbXref>Reactome:R-HSA-1226094</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9009282</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-1912391</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-174132</oboInOwl:hasDbXref>
        <oboInOwl:hasNarrowSynonym>cyclin-dependent kinase 6 activity</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasDbXref>Reactome:R-HSA-174251</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9929514</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-6805109</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-2220971</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9929717</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>cyclin-dependent protein kinase, intrinsic catalyst activity</oboInOwl:hasExactSynonym>
        <oboInOwl:hasNarrowSynonym>cyclin E kinase activity</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasNarrowSynonym>cdc2 kinase activity</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasDbXref>Reactome:R-HSA-380278</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-2468293</oboInOwl:hasDbXref>
        <oboInOwl:hasNarrowSynonym>cyclin D-dependent kinase activity</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9929482</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9929884</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9929720</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-5244669</oboInOwl:hasDbXref>
        <ns3:IAO_0000115>Cyclin-dependent catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.</ns3:IAO_0000115>
        <oboInOwl:hasDbXref>Reactome:R-HSA-4088024</oboInOwl:hasDbXref>
        <oboInOwl:hasAlternativeId>GO:0016537</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9929721</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-6797606</oboInOwl:hasDbXref>
        <oboInOwl:hasBroadSynonym>cyclin-dependent kinase activity</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>Reactome:R-HSA-69005</oboInOwl:hasDbXref>
        <oboInOwl:hasNarrowSynonym>cyclin-A associated kinase activity</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasDbXref>Reactome:R-HSA-188390</oboInOwl:hasDbXref>
        <oboInOwl:hasNarrowSynonym>cyclin-dependent kinase-2 activity</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasRelatedSynonym>CDK</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>Reactome:R-HSA-68944</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9624800</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EC:2.7.11.22</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9008412</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-5195402</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>ATP:cyclin phosphotransferase activity</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>Reactome:R-HSA-2468287</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-187948</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-2172183</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-4086410</oboInOwl:hasDbXref>
        <rdfs:comment>This reaction requires the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK).</rdfs:comment>
        <oboInOwl:hasDbXref>Reactome:R-HSA-2984220</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-174079</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9929532</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-2430533</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>Cdk-activating protein kinase activity</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>Reactome:R-HSA-2294600</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9929535</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-3788705</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>CDK, catalytic subunit activity</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9929935</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-6793661</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-180047</oboInOwl:hasDbXref>
        <oboInOwl:hasNarrowSynonym>neuronal cdc2-like kinase activity</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasNarrowSynonym>D-type cyclin kinase activity</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasDbXref>Reactome:R-HSA-187916</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-187959</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-2514854</oboInOwl:hasDbXref>
        <oboInOwl:hasNarrowSynonym>cyclin D-cdk6 kinase activity</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasOBONamespace>molecular_function</oboInOwl:hasOBONamespace>
        <oboInOwl:id>GO:0004693</oboInOwl:id>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9686521</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-174122</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-2990882</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-1226095</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-5692755</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-69227</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9929904</oboInOwl:hasDbXref>
        <skos:exactMatch rdf:resource="http://purl.uniprot.org/enzyme/2.7.11.22"/>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/GO_0097472 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/GO_0097472">
        <rdfs:label>cyclin-dependent protein kinase activity</rdfs:label>
    </Class>
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