protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity https://github.com/geneontology/go-ontology/issues/28176 Reactome:R-HSA-1168767 Reactome:R-HSA-879910 Catalysis of the reaction: ATP + protein L-tyrosine = ADP + protein L-tyrosine phosphate by a non-membrane spanning protein. Reactome:R-HSA-1112703 molecular_function ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity Reactome:R-HSA-1295519 janus kinase 2 activity Reactome:R-HSA-1112602 cytoplasmic protein tyrosine kinase activity non-specific protein-tyrosine kinase activity Reactome:R-HSA-6788582 EC:2.7.10.2 Bruton's tyrosine kinase activity p60c-src protein tyrosine kinase activity Reactome:R-HSA-8871373 GO:0004715 Reactome:R-HSA-1168459 janus kinase 1 activity Reactome:R-HSA-1369115 focal adhesion kinase activity Reactome:R-HSA-453200 janus kinase 3 activity Reactome:R-HSA-432148 Reactome:R-HSA-6786095 Reactome:R-HSA-6786096 Reactome:R-HSA-437936 Reactome:R-HSA-1168423 ATP:protein-tyrosine O-phosphotransferase activity