part of L-tryptophan biosynthetic process tryptophan synthase activity https://github.com/geneontology/go-ontology/issues/30193 GO:0004834 KEGG_REACTION:R02722 molecular_function EC:4.2.1.20 indoleglycerol phosphate aldolase activity Catalysis of the reaction: L-serine + (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate = L-tryptophan + glyceraldehyde 3-phosphate + H2O. MetaCyc:TRYPSYN-RXN RHEA:10532 L-tryptophan synthetase activity L-serine hydro-lyase [adding 1-C-(indol-3-yl)glycerol 3-phosphate; L-tryptophan and glyceraldehyde-3-phosphate-forming] tryptophan synthetase activity L-serine hydro-lyase (adding indoleglycerol-phosphate) tryptophan desmolase activity hydro-lyase activity