part of has part MAPK cascade MAP kinase scaffold activity https://github.com/geneontology/go-ontology/issues/14286 The binding activity of a molecule that functions as a physical support for the assembly of a multiprotein mitogen-activated protein kinase (MAPK) complex. Binds multiple kinases of the MAPKKK cascade, and also upstream signaling proteins, permitting those molecules to function in a coordinated way. Bringing together multiple enzymes and their substrates enables the signal to be transduced quickly and efficiently. MAP-kinase scaffold protein activity GO:0005078 molecular_function signaling adaptor activity mitogen-activated protein kinase binding protein complex scaffold activity