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    <!-- http://purl.obolibrary.org/obo/GO_0005243 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/GO_0005243">
        <rdfs:label>gap junction channel activity</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0022829"/>
        <oboInOwl:hasBroadSynonym>intercellular channel</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasRelatedSynonym>connexin</oboInOwl:hasRelatedSynonym>
        <ns3:IAO_0000115>A wide pore channel activity that enables a direct cytoplasmic connection from one cell to an adjacent cell. The gap junction can pass large solutes as well as electrical signals between cells. Gap junctions consist of two gap junction hemi-channels, or connexons, one contributed by each membrane through which the gap junction passes.</ns3:IAO_0000115>
        <oboInOwl:hasExactSynonym>innexin channel activity</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>Reactome:R-HSA-190681</oboInOwl:hasDbXref>
        <oboInOwl:id>GO:0005243</oboInOwl:id>
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        <oboInOwl:hasAlternativeId>GO:0015285</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>GO:0015286</oboInOwl:hasAlternativeId>
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    <!-- http://purl.obolibrary.org/obo/GO_0022829 -->

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        <rdfs:label>wide pore channel activity</rdfs:label>
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