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    <!-- http://purl.obolibrary.org/obo/GO_0007188 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/GO_0007188">
        <rdfs:label>adenylate cyclase-modulating G protein-coupled receptor signaling pathway</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/GO_0007189 -->

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        <rdfs:label>adenylate cyclase-activating G protein-coupled receptor signaling pathway</rdfs:label>
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        <oboInOwl:hasRelatedSynonym>positive regulation of adenylate cyclase activity by G-protein signalling pathway</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>GO:0007189</oboInOwl:id>
        <ns4:IAO_0000115>A G protein-coupled receptor signaling pathway in which the signal is transmitted via the activation of adenylyl cyclase activity which results in an increase in the intracellular concentration of cyclic AMP (cAMP). This pathway is negatively regulated by phosphodiesterase, which cleaves cAMP and terminates the signaling.</ns4:IAO_0000115>
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        <rdfs:comment>This term can be used to annotate ligands, receptors and G-proteins that lead to activation of adenylate cyclase activity within a signaling pathway.</rdfs:comment>
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        <oboInOwl:hasExactSynonym>GPCR signaling pathway via activation of adenylate cyclase activity</oboInOwl:hasExactSynonym>
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