2,4-dienoyl-CoA reductase (NADPH) activity https://github.com/geneontology/go-ontology/issues/28199 MetaCyc:RXN-20995 4-enoyl-CoA reductase (NADPH) activity RHEA:45232 trans-2,3-didehydroacyl-CoA:NADP+ 4-oxidoreductase activity RHEA:53296 4-enoyl-CoA reductase activity 4-enoyl-CoA reductase (NADPH2) RHEA:12136 4-enoyl coenzyme A (reduced nicotinamide adenine dinucleotide phosphate) reductase activity RHEA:53708 Catalysis of the reactions: a 4,5-saturated-(2E)-enoyl-CoA + NADP+ = a (2E,4E)-dienoyl-CoA + H+ + NADPH, and a (2E,4Z)-dienoyl-CoA + H+ + NADPH = a 4,5-saturated-(2E)-enoyl-CoA + NADP+. GO:0008670 EC:1.3.1.34 molecular_function MetaCyc:RXN-20994 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor