proton-translocating NAD(P)+ transhydrogenase activity https://github.com/geneontology/go-ontology/issues/27814 https://github.com/geneontology/go-ontology/issues/30193 EC:7.1.1.1 GO:0008750 molecular_function RHEA:47992 NAD(P)+ transhydrogenase (AB-specific) activity Catalysis of the reaction: H+(in) + NAD+ + NADPH = H+(out) + NADH + NADP+. proton transmembrane transporter activity oxidoreduction-driven active transmembrane transporter activity active monoatomic ion transmembrane transporter activity