serine-type endopeptidase activity obsolete signal peptidase I activity true GO:0009004 HOSP leader peptide hydrolase activity SPC OBSOLETE. Catalysis of the cleavage of N-terminal leader sequences from secreted and periplasmic proteins precursor. leader proteinase activity signal peptide hydrolase activity prokaryotic signal proteinase propeptidase activity eukaryotic signal proteinase phage-procoat-leader peptidase activity signalase activity prokaryotic leader peptidase PuIO prepilin peptidase SPase I activity prokaryotic signal peptidase signal proteinase activity This term was made obsolete because it represents a gene product. pilin leader peptidase molecular_function bacterial leader peptidase I activity leader peptidase I Escherichia coli leader peptidase leader peptidase activity bacterial leader peptidase 1 eukaryotic signal peptidase signal peptidase I activity