coenzyme A metabolic process coenzyme A biosynthetic process https://github.com/geneontology/go-ontology/issues/28527 MetaCyc:PWY-8342 MetaCyc:PANTOSYN-PWY MetaCyc:COA-PWY-1 MetaCyc:PWY-7851 MetaCyc:PWY-4221 coenzyme A biosynthesis GO:0006764 biological_process coenzyme A anabolism MetaCyc:COA-PWY CoA biosynthesis MetaCyc:PWY8J2-29 GO:0015937 coenzyme A formation coenzyme A synthesis The chemical reactions and pathways resulting in the formation of coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester. Reactome:R-HSA-196783 sulfur compound biosynthetic process purine-containing compound biosynthetic process nucleoside phosphate biosynthetic process