nucleotide biosynthetic process bis(5'-nucleosidyl) oligophosphate biosynthetic process bis(5'-nucleosidyl) oligophosphate anabolism bis(5'-nucleosidyl) oligophosphate formation biological_process bis(5'-nucleosidyl) oligophosphate biosynthesis GO:0015957 The chemical reactions and pathways resulting in the formation of a bis(5'-nucleosidyl) oligophosphate, a compound formed of two nucleosides joined together through their 5' carbons by a chain of phosphate molecules. bis(5'-nucleosidyl) oligophosphate synthesis