acyl-CoA hydrolase activity https://github.com/geneontology/go-ontology/issues/26441 https://github.com/geneontology/go-ontology/issues/30193 RHEA:70415 RHEA:70411 RHEA:40591 Reactome:R-HSA-193385 RHEA:45716 RHEA:70419 RHEA:40595 RHEA:78267 RHEA:49444 RHEA:66704 RHEA:46224 RHEA:70331 RHEA:59936 RHEA:40575 molecular_function RHEA:38291 Catalysis of the reaction: an acyl-CoA + H2O = a carboxylate + CoA + H+. RHEA:28542 RHEA:31511 RHEA:70427 RHEA:19741 RHEA:70423 GO:0016289 RHEA:40583 CoA hydrolase activity RHEA:40587 RHEA:40219 thiolester hydrolase activity deacylase activity