part of 1-phosphatidylinositol-3-kinase activity https://github.com/geneontology/go-ontology/issues/28336 https://github.com/geneontology/go-ontology/issues/30193 Reactome:R-HSA-1675961 Reactome:R-HSA-1433514 GO:0016303 PI3-kinase activity PtdIns-3-kinase activity Reactome:R-HSA-9670433 phosphatidylinositol 3-kinase activity, class III phosphatidylinositol 3-kinase activity, class II GO:0004429 Reactome:R-HSA-6798174 KEGG_REACTION:R03362 1-phosphatidylinositol 3-kinase activity Reactome:R-HSA-1676024 phosphatidylinositol 3-kinase activity, class I type I phosphatidylinositol kinase activity molecular_function PI3K EC:2.7.1.137 type III phosphoinositide 3-kinase activity MetaCyc:1-PHOSPHATIDYLINOSITOL-3-KINASE-RXN Catalysis of the reaction: a 1-phosphatidyl-1D-myo-inositol + ATP = a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ADP + H+. Reactome:R-HSA-1675939 Reactome:R-HSA-2045911 RHEA:12709 Reactome:R-HSA-109699 Reactome:R-HSA-5672012 Reactome:R-HSA-9680389 phosphatidylinositol 3-kinase, class I, catalyst activity phosphatidylinositol-3-phosphate biosynthetic process phosphatidylinositol kinase activity