(3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity long-chain (3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity https://github.com/geneontology/go-ontology/issues/26445 https://github.com/geneontology/go-ontology/issues/30193 https://github.com/geneontology/go-ontology/issues/30577 While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283). RHEA:84427 MetaCyc:1.1.1.211-RXN long-chain 3-hydroxyacyl coenzyme A dehydrogenase activity RHEA:82931 RHEA:84679 molecular_function EC:1.1.1.211 RHEA:84675 LCHAD RHEA:84671 RHEA:47440 GO:0016509 RHEA:83379 RHEA:83215 RHEA:83139 RHEA:78731 RHEA:31167 RHEA:83363 RHEA:85131 RHEA:82999 RHEA:47456 RHEA:78739 beta-hydroxyacyl-CoA dehydrogenase activity Catalysis of the reaction: a long-chain (3S)-3-hydroxy fatty acyl-CoA + NAD+ = a long-chain 3-oxo-fatty acyl-CoA + H+ + NADH. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons. long-chain-(S)-3-hydroxyacyl-CoA:NAD+ oxidoreductase activity RHEA:47428 long-chain-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity RHEA:84415 RHEA:83031 RHEA:84411 RHEA:83395 RHEA:83079 RHEA:84691 RHEA:31159 RHEA:52656 RHEA:78727