enoyl-CoA hydratase activity 3-hydroxyacyl-CoA dehydratase activity https://github.com/geneontology/go-ontology/issues/24738 https://github.com/geneontology/go-ontology/issues/28557 https://github.com/geneontology/go-ontology/issues/29788 RHEA:84403 RHEA:45992 RHEA:30547 RHEA:84407 EC:4.2.1.74 Reactome:R-HSA-8957389 RHEA:39123 RHEA:82995 RHEA:83323 Reactome:R-HSA-2066778 molecular_function RHEA:84659 RHEA:52664 RHEA:39139 Reactome:R-HSA-389986 RHEA:84667 RHEA:47436 RHEA:84663 RHEA:83211 MetaCyc:ENOYL-COA-HYDRAT-RXN RHEA:40207 RHEA:82923 RHEA:76647 RHEA:84395 RHEA:83063 RHEA:85127 RHEA:47424 RHEA:84399 Reactome:R-HSA-5676637 RHEA:83067 EC:4.2.1.150 RHEA:33767 RHEA:31199 RHEA:78559 RHEA:72579 RHEA:31075 RHEA:31191 RHEA:40187 RHEA:71647 RHEA:83359 RHEA:47452 Reactome:R-HSA-390252 RHEA:35359 RHEA:78575 RHEA:78603 GO:0018812 Catalysis of the reaction: a 3-hydroxy-fatty acyl-CoA = a (2E)-enoyl-CoA + H2O. RHEA:16105 RHEA:31163 RHEA:46352 RHEA:82959 RHEA:31171 RHEA:46348 RHEA:78591 RHEA:83375 Reactome:R-HSA-2066780 RHEA:84627 Reactome:R-HSA-6809263 RHEA:35347 RHEA:83147 RHEA:83027 RHEA:84631 RHEA:35355 RHEA:78911 RHEA:78915 RHEA:83391