oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor trans-2-enoyl-CoA reductase (NADPH) activity https://github.com/geneontology/go-ontology/issues/30193 reductase, trans-enoyl coenzyme A RHEA:39443 RHEA:39563 RHEA:35367 RHEA:39527 RHEA:39203 RHEA:39367 RHEA:39403 RHEA:35363 RHEA:39191 RHEA:39391 RHEA:39551 RHEA:35351 RHEA:39275 RHEA:39355 NADPH-dependent trans-2-enoyl-CoA reductase activity RHEA:39515 RHEA:39239 RHEA:39319 RHEA:39479 Reactome:R-HSA-8952873 GO:0019166 RHEA:39263 RHEA:33763 RHEA:39427 RHEA:39503 RHEA:39307 RHEA:39467 acyl-CoA:NADP+ trans-2-oxidoreductase activity RHEA:39227 EC:1.3.1.38 RHEA:39347 Reactome:R-HSA-6809810 RHEA:39331 Catalysis of the reaction: acyl-CoA + NADP+ = trans-2,3-dehydroacyl-CoA + NADPH + H+. RHEA:36143 RHEA:39179 RHEA:39491 RHEA:39251 molecular_function RHEA:39415 RHEA:39539 Reactome:R-HSA-6786720 RHEA:39379 RHEA:39455 MetaCyc:TRANSENOYLCOARED-RXN RHEA:39215