fatty acid metabolic process icosanoid metabolic process lipoxygenase pathway The chemical reactions and pathways by which an unsaturated fatty acid (such as arachidonic acid or linolenic acid) is converted to other compounds, and in which the first step is hydroperoxide formation catalyzed by lipoxygenase. Reactome:R-HSA-2142770 GO:0019372 Reactome:R-HSA-2142688 Reactome:R-HSA-2142712 biological_process Reactome:R-HSA-9025094