receptor guanylyl cyclase signaling pathway G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger obsolete cGMP-mediated signaling https://github.com/geneontology/go-ontology/issues/30803 true biological_process OBSOLETE. An intracellular signaling cassette that starts with production of cyclic GMP (cGMP), and ends with activation of downstream effectors that further transmit the signal within the cell. This term was obsoleted because it was not clearly defined. Several pathways use cGMP; consider: receptor guanylyl cyclase signaling pathway ; GO:0007168, nitric oxide-cGMP-mediated signaling ; GO:0038060 or G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger ; GO:0007199. cGMP-mediated signalling GO:0019934 nitric oxide-cGMP-mediated signaling