part of midbrain-hindbrain boundary structural organization biological_process MHB structural organization isthmus structural organization midbrain-hindbrain boundary structural organisation The process that contributes to the act of creating the structural organization of the midbrain-hindbrain boundary structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate. GO:0021552 midbrain-hindbrain boundary morphogenesis anatomical structure arrangement