part of muscle contraction muscle filament sliding The sliding of actin thin filaments and myosin thick filaments past each other in muscle contraction. This involves a process of interaction of myosin located on a thick filament with actin located on a thin filament. During this process ATP is split and forces are generated. biological_process Reactome:R-HSA-390522 GO:0030049 actin-myosin filament sliding