vacuolar membrane obsolete integral component of vacuolar membrane https://github.com/geneontology/go-ontology/issues/23424 true GO:0031166 integral to vacuolar membrane This term was obsoleted because it represents protein topology, not a cellular component. OBSOLETE. The component of the vacuolar membrane consisting of gene products and protein complexes that have some part that penetrates at least one leaflet of the membrane bilayer. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. cellular_component