happens during mitotic S phase mitotic intra-S DNA damage checkpoint signaling https://github.com/geneontology/go-ontology/issues/20935 GO:0031573 signal transduction involved in intra-S DNA damage checkpoint mitotic intra-S DNA damage checkpoint S-phase checkpoint biological_process GO:0072428 intra-S DNA damage checkpoint A mitotic cell cycle checkpoint that slows DNA synthesis in response to DNA damage by the prevention of new origin firing and the stabilization of slow replication fork progression. mitotic DNA damage checkpoint signaling