RNA nuclease activity hydrolase activity, acting on ester bonds double-stranded RNA-specific ribonuclease activity https://github.com/geneontology/go-ontology/issues/24408 molecular_function dsRNA-specific RNase activity double-stranded RNA-specific RNase activity dsRNA-specific ribonuclease activity GO:0032296 Catalysis of the hydrolysis of phosphodiester bonds in double-stranded RNA molecules.