fatty acid beta-oxidation obsolete fatty acid beta-oxidation, unsaturated, even number, reductase/isomerase pathway https://github.com/geneontology/go-ontology/issues/31932 true GO:0033543 OBSOLETE. A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on even-numbered carbons are degraded. In this pathway, the intermediate 2,4-dienoyl-CoA is converted to trans-2-enoyl-CoA by 2,4-dienoyl-CoA reductase and delta3-delta2-enoyl-CoA isomerase; trans-2-enoyl-CoA returns to the core beta-oxidation pathway for further degradation. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively). biological_process This term was obsoleted because it represents a specific pathway variant, which is out of scope for GO.