has part glutamate-gated receptor activity glutamate receptor signaling pathway ionotropic glutamate receptor signaling pathway biological_process GO:0035235 ionotropic glutamate receptor signalling pathway The series of molecular signals initiated by glutamate binding to a glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex, and ending with the regulation of a downstream cellular process, e.g. transcription. ligand-gated ion channel signaling pathway