AP-2 adaptor complex binding GO:0035612 Binding to an AP-2 adaptor complex. The AP-2 adaptor complex is a heterotetrameric AP-type membrane coat adaptor complex that consists of alpha, beta2, mu2 and sigma2 subunits and links clathrin to the membrane surface of a vesicle. In at least humans, the AP-2 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different alpha genes (alphaA and alphaC). molecular_function bf AP-2 clathrin adaptor complex binding 2010-11-25T03:51:17Z protein-containing complex binding