part of neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0036483 endoplasmic reticulum stress-induced neuron apoptosis endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a neuron. The pathway is induced in response to a stimulus indicating endoplasmic reticulum (ER) stress, and ends when the execution phase of apoptosis is triggered. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen. biological_process ER stress-induced neuron apoptosis ER stress-induced neuron intrinsic apoptotic signaling pathway bf 2014-08-14T13:33:23Z neuron apoptotic process intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress