symbiont-mediated suppression of host PKR/eIFalpha signaling https://github.com/geneontology/go-ontology/issues/21971 https://github.com/geneontology/go-ontology/issues/26686 https://github.com/geneontology/go-ontology/issues/26918 GO:0039580 VZ:554 suppression by virus of host EIF2AK2 activity A process in which a symbiont inhibits or disrupts host PKR (Protein Kinase regulated by RNA) signaling. PKR phosphorylates host targets such as the translation initiation factor eIF2alpha that inhibits protein synthesis as an antimicrobial response. Inhibition of host PKR signaling maintains the host ability to translate mRNA. The host is defined as the larger of the organisms involved in a symbiotic interaction. biological_process suppression by virus of host PKR activity bf suppression by virus of host PKR signaling symbiont-mediated suppression of host signal transduction pathway symbiont-mediated suppression of host-directed shutoff of host translation