epinephrine metabolic process epinephrine catabolic process GO:0042419 The chemical reactions and pathways resulting in the breakdown of epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine. epinephrine degradation epinephrine catabolism adrenaline catabolism biological_process epinephrine breakdown adrenaline catabolic process catecholamine catabolic process