NADPH oxidase complex https://github.com/geneontology/go-ontology/issues/29068 cellular_component A enzyme complex of which the core is a heterodimer composed of a light (alpha) and heavy (beta) chain, and requires the cytosolic regulatory subunits at least NCF1/p47-phox, NCF2/p67-phox, NCF4/p40-phox and the small GTPase RAC1 or RAC2 for activity. Functions in superoxide generation by the NADPH-dependent reduction of O2. GO:0043020 respiratory-burst oxidase flavocytochrome b558 plasma membrane protein complex oxidoreductase complex