histone H2B acetyltransferase activity histone H2BK12 acetyltransferase activity https://github.com/geneontology/go-ontology/issues/28368 https://github.com/geneontology/go-ontology/issues/28520 https://github.com/geneontology/go-ontology/issues/30180 https://github.com/geneontology/go-ontology/issues/30578 histone lysine N-acetyltransferase activity (H2B-K12 specific) GO:0044015 histone H2B-K12 acetyltransferase activity histone acetyltransferase activity (H2B-K12 specific) Note that the residue position corresponds to the canonical human H2B histone (UniProtKB:P62807); the N-terminus of histone H2B is divergent across eukaryotes; make sure that the paper clearly references the human protein for the position of this modification to use this term. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary across different genes within an organism. molecular_function Catalysis of the reaction: acetyl-CoA + histone H2B L-lysine (position 12) = CoA + histone H2B N6-acetyl-L-lysine (position 12). histone acetylase activity (H2B-K12 specific)