part of ubiquitin ligase complex organelle membrane Dsc E3 ubiquitin ligase complex jl GO:0044695 2012-08-16T13:41:48Z An E3 ubiquitin ligase complex localized to the ER and Golgi membrane. In fission yeast comprises Dsc1, 2, 3 and 4. Involved in the processes of fission yeast sre1 (human SREBP) transcriptional activator proteolytic cleavage, the multivesicular body (MVB) pathway, and a post-endoplasmic reticulum pathway for protein catabolism. cellular_component membrane protein complex