double-stranded DNA binding hemi-methylated DNA-binding 2012-10-24T14:58:14Z jl molecular_function GO:0044729 Binding to double-stranded hemi-methylated DNA at replication foci (one strand methylated, while the other strand is unmethylated). Methylation of cytosine or adenine in DNA is an important mechanism for establishing stable heritable epigenetic marks. double-stranded hemi-methylated DNA binding