has part fatty-acyl-CoA synthase activity acetate metabolic process versicolorin reductase activity mycotoxin biosynthetic process aflatoxin biosynthetic process aflatoxin anabolism GO:0045122 aflatoxin formation aflatoxin biosynthesis The chemical reactions and pathways resulting in the formation of aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450. biological_process aflatoxin synthesis aflatoxin metabolic process versicolorin B synthase activity demethylsterigmatocystin 6-O-methyltransferase activity sterigmatocystin 7-O-methyltransferase activity norsolorinate anthrone synthase activity norsolorinic acid ketoreductase activity averantin hydroxylase activity 5'-hydroxyaverantin dehydrogenase activity versiconal hemiacetal acetate esterase activity versicolorin B desaturase activity aflatoxin B synthase activity