tricarboxylic acid cycle heteromeric enzyme complex alpha-ketoacid dehydrogenase complex oxoglutarate dehydrogenase complex https://github.com/geneontology/go-ontology/issues/26122 https://github.com/geneontology/go-ontology/issues/26881 https://github.com/geneontology/go-ontology/issues/29951 dihydrolipoamide S-succinyltransferase complex cellular_component The catalytic activities of the individual components of this complex are represented by the molecular function terms 'oxoglutarate dehydrogenase (succinyl-transferring) activity ; GO:0004591' (E1), 'dihydrolipoyllysine-residue succinyltransferase activity ; GO:0004149' (E2), and 'dihydrolipoyl dehydrogenase activity ; GO:0004148' (E3). A multi-enzyme complex that catalyzes the oxidative decarboxylation of alpha-ketoglutarate (also known as 2-oxoglutarate) to form succinyl-CoA. The complex comprises multiple copies of three enzymes referred to as E1, E2 and E3: oxoglutarate dehydrogenase (lipoamide) (E1), dihydrolipoamide S-succinyltransferase (E2) and dihydrolipoamide dehydrogenase (E3). Additional proteins may also be present. Wikipedia:Oxoglutarate_dehydrogenase_complex alpha-ketoglutarate dehydrogenase complex KGDHC GO:0045252 transferase complex