oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 15-oxoprostaglandin 13-reductase [NAD(P)+] activity https://github.com/geneontology/go-ontology/issues/28134 https://github.com/geneontology/go-ontology/issues/30105 15-oxoprostaglandin 13-oxidase [NAD(P)+] activity RHEA:11912 RHEA:11916 Reactome:R-HSA-2161692 molecular_function KEGG_REACTION:R04556 EC:1.3.1.48 MetaCyc:15-OXOPROSTAGLANDIN-13-REDUCTASE-RXN 15-oxoprostaglandin 13-oxidase activity KEGG_REACTION:R04557 Catalysis of the reaction: 13,14-dihydro-15-oxo-prostaglandin E2 + NAD(P)+ = 15-oxoprostaglandin E2 + H+ + NAD(P)H. GO:0047522 (5Z)-(15S)-11alpha-hydroxy-9,15-dioxoprostanoate:NAD(P)+ delta13-oxidoreductase activity 15-oxo-Delta(13)-prostaglandin reductase activity