oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen arachidonate 8(R)-lipoxygenase activity https://github.com/geneontology/go-ontology/issues/30193 8(R)-lipoxygenase activity molecular_function MetaCyc:ARACHIDONATE-8-LIPOXYGENASE-RXN KEGG_REACTION:R01594 GO:0047677 arachidonate:oxygen 8-oxidoreductase activity arachidonate 8-lipoxygenase activity 8-lipoxygenase activity This activity produces the R-enantiomer of HPETE, 8(R)-HPETE. For the reaction producing the S-enantiomer, see GO:0036403. EC:1.13.11.40 Catalysis of the reaction: arachidonate + O2 = (5Z,8R,9E,11Z,14Z)-8-hydroperoxyicosa-5,9,11,14-tetraenoate. RHEA:14985