CoA-ligase activity cholate-CoA ligase activity https://github.com/geneontology/go-ontology/issues/30193 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoate-CoA synthetase activity 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate--CoA ligase activity cholic acid:CoA ligase activity cholate thiokinase activity cholate:CoA ligase (AMP-forming) 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate-CoA ligase activity RHEA:47136 BAL activity 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl coenzyme A synthetase activity GO:0047747 choloyl coenzyme A synthetase activity 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanate-CoA ligase activity THCA-CoA ligase activity 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate:CoA ligase (AMP-forming) activity 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate-CoA ligase activity 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoate-CoA ligase activity RHEA:22976 cholyl-CoA synthetase activity choloyl-CoA synthetase activity 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate-CoA synthetase activity 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl coenzyme A synthetase activity cholic thiokinase activity MetaCyc:CHOLATE--COA-LIGASE-RXN Catalysis of the reactions: (1) ATP + cholate + CoA = AMP + diphosphate + choloyl-CoA and (2) ATP + (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate + CoA = AMP + diphosphate + (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA. This reaction is the first step in the conjugation of bile acids with amino acids, converting bile acids into their acyl-CoA thioesters. Chenodeoxycholate, deoxycholate, lithocholate and trihydroxycoprostanoate can also act as substrates. RHEA:43764 RHEA:23532 molecular_function 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanate:CoA ligase (AMP-forming) RHEA:47128 trihydroxycoprostanoyl-CoA synthetase activity bile acid coenzyme A ligase activity bile acid CoA ligase activity EC:6.2.1.7 GO:0047477